Clinical study of the usefulness of MMC intravesical infusion therapy soon after nephroureterectomy in patients with urothelial carcinoma of upper urinary tract

Clinical study of the usefulness of MMC intravesical infusion therapy soon after nephroureterectomy in patients with urothelial carcinoma of upper urinary tract - Clinical study of the usefulness of MMC intravesical infusion therapy soon after nephroureterectomy in patients with urothelial carcinoma of upper urinary tract

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020365

Enrollment

Registered

2016-02-01

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper urinary tract urotherial tumors.

Interventions

mitomycin C immediate bladder infusion therapy MMC40mg mixed with saline40ml is administered to 30 minutes in the bladder within 48 hours after surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients is diagnosed with upper urinary tract urotherial tumor in tissue biopsy in ureteroscopy 2.Patient's upper urinary tract urotherial tumor is significant in image 3.Patien's classification urine cytology is positive 4.Following 1 or 2 or 3, nephroureterectomy is emforced 5.Patient's agreement is obtained in a document about participation of this trial

Exclusion criteria

Exclusion criteria: 1.Both upper urinary tract urotherial tumor 2.History of bladder tumor 3.history of neo-adjuvant chemotherapy 4.Patient can't voiding

Design outcomes

Primary

Measure	Time frame
Bladder recurrence rate Evaluated at the cystoscope of every three months after the administration , conduct the longest two years observation	—

Countries

Japan

Contacts

Public ContactShin Kobayashi

Asahikawa medical univercity Department of Urology

shinkoba@asahikawa-med.ac.jp0166-65-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026