Efficacy and safety of cidofovir for recurrent respiratory papillomatosis (2)

Efficacy and safety of cidofovir for recurrent respiratory papillomatosis (2) - Cidofovir for recurrent respiratory papillomatosis (2)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020343

Enrollment

Registered

2015-12-25

Start date

2012-04-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent respiratory papillomatosis

Interventions

Intralesional injection of 3 to 5 mL of 7.5 mg/mL cidofovir under general anesthesia is biweekly performed three times.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with recurrent respiratory papillomatosis who previously received laryngeal surgery

Exclusion criteria

Exclusion criteria: Patients with severe renal or liver dysfunction, with a risk for general anesthesia, or whom a doctor considered not eligible

Design outcomes

Primary

Measure	Time frame
Progression-free duration of recurrent respiratory papillomatosis based on Derkay's severity score	—

Secondary

Measure	Time frame
Hematological disorders evaluated by grade od adverse events using CTCAE ver 3.0	—

Countries

Japan

Contacts

Public ContactYosuke Nakanishi

Kanazawa University Otolaryngology-Head and Neck Surgery

nakanish@med.kanazawa-u.ac.jp076-265-2413

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026