Oral fat tolerance test for sitosterolemia and familial hypercholesterolemia

Oral fat tolerance test for sitosterolemia and familial hypercholesterolemia - OFTT for sitosterolemia and familial hypercholesterolemia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020330

Enrollment

Registered

2015-12-24

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sitosterolemia Familial Hypercholesterolemia

Interventions

OFTT cream (50g/body surface area square meter, orally only once)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age 6yr or greater Patient who can provide written informed consent Outpatient at Kanazawa University Hospital

Exclusion criteria

Exclusion criteria: Anemia Lactose intolerance Allergy for the content(s) of OFTT cream Immunosuppressive therapy Myocardial infarction or unstable angina Liver dysfunction (AST or ALT 100 IU/L or greater) Renal dysfunction(BUN 25 mg/dL or greater, or Cr 2.0 mg/dL or greater) Female with pregnancy or expected Patient whose doctor in charge consider it inappropriate to participate

Design outcomes

Primary

Measure	Time frame
RLP cholesterol(Before, 2hr, 4hr, 6hr)	—

Secondary

Measure	Time frame
Total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, RLP triglyceride, sitosterol, lathosterol, campesterol, APOA-1, APOA-2, APOB, APOC-2, APOC-3, APOE (Before, 2hr, 4hr, 6hr)	—

Countries

Japan

Contacts

Public ContactHayato Tada

Kanazawa University Hospital Department of emergency medicine

ht240z@sa3.so-net.ne.jp076-265-2000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026