Small intestinal Crohn'
Conditions
Interventions
During the registration period from May 12, 2015, to March 31, 2023, the patients undergo a maximum of six intestinal mucosal biopsies, mucosal scrapes, and aspiration of intestinal juice at the doubl
Sponsors
Department of Medicine, Division of Gastroenterology, Jichi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with small intestinal Crohn's disease or the other small intestinal diseases requiring double-balloon endoscopy with written informed consent
Exclusion criteria
Exclusion criteria: Patients under poor conditions as follows: acute abdomen, ileus, bowel perforation, pancreatitis, respiratory disease, heart disease, hemophilia, patients with too large intestinal ulcers or tumors Patients with acute severe inflammation Patients with abnormal coagulopathy Pregnant patients or patients during breast feeding Contraindication of bowel cleansing agent Patients who are considered inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Data of the bacterial 16S rRNA by next-generation sequencer | — |
Secondary
| Measure | Time frame |
|---|---|
| Data of the intestinal immune cells by flow cytometry (animal experiments) | — |
Countries
Japan
Contacts
Public ContactManabu Nagayama
Jichi Medical University Department of Medicine, Division of Gastroenterology
Outcome results
None listed