Liver cirrhosis Patients with HCV infection
Conditions
Interventions
None listed
Sponsors
Hokkaido University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [1] Patients who are 20 years of age or older at the time of informed consent [2] Patients who have been fully informed and have provided written informed consent to participate in this study prior to study initiation [3] Patients with a chronic HCV infection who do not meet any of the following exclusion criteria
Exclusion criteria
Exclusion criteria: 1) Patients with poorly controlled cardiac disease (e.g., myocardial infarction, cardiac failure, arrhythmia) 2) Patients with severe hepatic impairment 3) Patients with a concurrent malignancy, including hepatocellular carcinoma, at the start of treatment 4) Patients who are unsuitable, in the opinion of the principal investigator, for this study due to any other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of serum HCV titer | — |
Secondary
| Measure | Time frame |
|---|---|
| ) Change of oxidant stress maker and blood biochemistry 2) Presence or absence of a reversal of liver fibrosis 3) Presence or absence of an improvement in AFP levels 4) Effects of glucose/lipid-related factors on treatment response 5) Incidence of AEs | — |
Countries
Japan
Contacts
Public ContactGoki Suda
Hokkaido University Department of Gastroenterology and Hepatology, Graduate School of Medicine,
Outcome results
None listed