Metabolome analysis in association with the effects of Inchinkoto, a herbal medicine.

Metabolome analysis in association with the effects of Inchinkoto, a herbal medicine. - Metabolome analysis in association with the effects of Inchinkoto.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020274

Enrollment

Registered

2016-04-01

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients who undergo percutaneous transhepatic biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD) due to biliary obstruction. Among the, patients who were included the study &quot

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients who undergo transhepatic biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD) due to obstructive jaundice. 2. Patients who agree to participate this study. Note; patients who are undergoing antibiotics therapy such as Chloramphenicol will not be excluded.

Exclusion criteria

Exclusion criteria: 1. Patients who do not agree to participate this study. 2. Patients who are not eligible to participate this study (determined by chief or associate doctors who are responsible to perform this study. 3. Patients who are allergic to Inchinkoto. 4. Patients who are taking choleretic drugs such as ulsodeoxycholic acid.

Design outcomes

Primary

Measure	Time frame
Alternation of metabolome after an oral intake of Inchinkoto.	—

Secondary

Measure	Time frame
The association between the serum concentrations of genipin, geniposide, and 6,7-dimetylesculetin and the biliary concentrations of total bilirubin, direct bilirubin, and bile acid.	—

Countries

Japan

Contacts

Public Contactyukihiro yokoyama

Nagoya University Hospital Surgery 1

yyoko@med.nagoya-u.ac.jp+81527442222

Outcome results