Adult patients who were intended for elective major cardiovascular surgery (coronary artery bypass surgery, valvular surgery, aortic surgery, or combined surgery)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 20 and over 2. Patients who were intended for elective major cardiovascular surgery
Exclusion criteria
Exclusion criteria: 1. Patients with chronic renal failure 2. Patients with peripheral arterial disease 3. Patients with a previous history of psychiatric disease 4. Patients with a previous history of neuromuscular disease 5. Patinets with cognitive impairment before surgery (Mini-Mental State Examination <18 points) 6. Patients with intubation beyond 24h after surgery 7. Patients who received reoperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the concentration of 3-MH in 24 hours urine corrected for urinary creatinine content from postoperative day 1 to 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| knee extensor isometric strength handgrip strength | — |
Countries
Japan
Contacts
Nagoya University Graduate school of Medicine