Skip to content

Feasibility and effectiveness of electrical stimulation as countermeasure against muscle proteolysis after cardiovascular surgery

Feasibility and effectiveness of electrical stimulation as countermeasure against muscle proteolysis after cardiovascular surgery - Feasibility and effectiveness of electrical stimulation as countermeasure against muscle proteolysis after cardiovascular surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000020221
Enrollment
100
Registered
2015-12-16
Start date
2011-11-23
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult patients who were intended for elective major cardiovascular surgery (coronary artery bypass surgery, valvular surgery, aortic surgery, or combined surgery)

Interventions

Electrical muscle stimulation and postoperative mobilization program Electrical muscle stimulation: implemented on bilateral quadriceps and triceps surae muscles for 30-60 minutes daily from postoper

Sponsors

Nagoya University Graduate school of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged 20 and over 2. Patients who were intended for elective major cardiovascular surgery

Exclusion criteria

Exclusion criteria: 1. Patients with chronic renal failure 2. Patients with peripheral arterial disease 3. Patients with a previous history of psychiatric disease 4. Patients with a previous history of neuromuscular disease 5. Patinets with cognitive impairment before surgery (Mini-Mental State Examination <18 points) 6. Patients with intubation beyond 24h after surgery 7. Patients who received reoperation

Design outcomes

Primary

MeasureTime frame
the concentration of 3-MH in 24 hours urine corrected for urinary creatinine content from postoperative day 1 to 5

Secondary

MeasureTime frame
knee extensor isometric strength handgrip strength

Countries

Japan

Contacts

Public ContactYAMADA SUMIO

Nagoya University Graduate school of Medicine

yamadas@met.nagoya-u.ac.jp052-719-1349

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026