To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET (s-DET) compared to those of the conventional DET (c-DET) in Assisted Reproductive Technology (ART) treatment

To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET (s-DET) compared to those of the conventional DET (c-DET) in Assisted Reproductive Technology (ART) treatment - To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020219

Enrollment

500

Registered

2015-12-16

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Some patients underwent s-DET in which two embryos were transferred separately. Other patients underwent c-DET in which two embryos were transferred together.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Study patients are selected if they are eligible for in vitro fertilization (IVF)/ET and had a history of two or more failed IVF/ET cycles with morphologically and developmentally average to good quality embryos transferred into an adequately prepared endometrium.

Exclusion criteria

Exclusion criteria: None of the patients have submucosal fibroids, endometrial polyps, intrauterine adhesions, congenital anomalies of the uterus, or hydrosalpinges. In addition, none of the patients have any history of or an active autoimmune disease.

Design outcomes

Primary

Measure	Time frame
Reproductive outcomes including human chorionic gonadotropin levels, gestational sac development, and clinical pregnancy, implantation, multiple pregnancy, and miscarriage rates were compared between the s-DET and c-DET groups.	—

Countries

Japan

Contacts

Public ContactTOMOYA HASEGAWA

Tokyo Medical University Department of Obstetrics and Gynecology

ppppq999@gmail.com03-3342-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026