Skip to content

Study on safety and efficacy of cetuximab in locally advanced, recurrent and/or metastatic oral cancer

Study on safety and efficacy of cetuximab in locally advanced, recurrent and/or metastatic oral cancer - Safety and efficacy of cetuximab in oral cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000020218
Enrollment
300
Registered
2015-12-16
Start date
2015-12-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral cancer

Interventions

None listed

Sponsors

Nagasaki University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The subjects must meet all the following criteria. 1. Malignant tumors originated from the oral cavity. 2. Confirmed that a histopathological malignant. 3. In locally advanced cases, the cases in UICC 7th edition stage III / IV, or recurrent and/or metastatic cases with not indicated for local therapy. 4. Received any of the therapies described below. i) Radiation therapy (at least 60Gy) ii) Some chemotherapy 5. Age at the time of registration at least 20 years of age 6. Performance status: 0-2 7. December 21, 2012 or later, the case that the treatment of cetuximab has been started.

Exclusion criteria

Exclusion criteria: Patients also applicable in one of the following are excluded as a target. 1. Cases with cetuximab treatment to December 20, 2012 or earlier. 2. Cases with complications in life prognosis in addition to oral cancer. 3. Cases with active double cancer. However, gastric cancer was cured by carcinoma in situ, or endoscopic mucosal resection that is judged to be cured with local treatment, esophageal cancer, colorectal cancer, such as pM it is not included in the activities of the overlapping cancer. 4. Other, patients principal investigator has determined to be inappropriate as a subject.

Design outcomes

Primary

MeasureTime frame
Adverse events, 1-year progression-free survival and 1-year survival rate.

Countries

Japan

Contacts

Public ContactSouichi Yanamoto

Nagasaki University Hospital, Dentistry for Medically Compromised Patient

syana@nagasaki-u.ac.jp095-819-7698

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026