Effect of lactoferrin ingestion on norovirus infection of food service employees: a randomized, double-blind, placebo-controlled trial.

Effect of lactoferrin ingestion on norovirus infection of food service employees: a randomized, double-blind, placebo-controlled trial. - Effect of lactoferrin ingestion on norovirus infection of food service employees: a randomized, double-blind, placebo-controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020100

Enrollment

150

Registered

2015-12-07

Start date

2015-12-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Norovirus infection

Interventions

Ingestion of lactoferrin for 15 days Ingestion of placebo for 15 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects in a food service company outsourcing norovirus test to Tokyo Kenbikyoin. 2) Subjects test positive for norovirus more than 3 days after disappearance of gastroenteritis symptoms

Exclusion criteria

Exclusion criteria: 1) Subjects with milk allergy 2) Subjects under 20 years old 3) Subjects in pregnancy 4) Subjects who plan to retire during trial period 5) Subjects who have a history of serious disorders in liver, kidney, heart, lung, gastro-intestine, blood, endocrine system, or metabolic system etc 6) Subjects who consume lactoferrin habitually 7) Subject who are judged inappropriate to this trial by the investigator

Design outcomes

Primary

Measure	Time frame
Norovirus infection	—

Secondary

Measure	Time frame
Relapses of gastroenteritis symptoms	—

Countries

Japan

Contacts

Public ContactTakeshi Ito

Incorporated Foundation Tokyo Kenbikyoin Director

ito-t@umin.ac.jp03-3534-2970

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026