The Usefulness and Hemodynamic Effect of Landiolol Treatment to Control Atrial Tachyarrhythmia in Patients with Heart Failure with Reduced Ejection Fraction in The Acute Phase

The Usefulness and Hemodynamic Effect of Landiolol Treatment to Control Atrial Tachyarrhythmia in Patients with Heart Failure with Reduced Ejection Fraction in The Acute Phase - Landiolol for ADHF with HFrEF

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020084

Enrollment

100

Registered

2015-12-07

Start date

2013-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients with heart failure with reduced ejection fraction(EF&lt

Interventions

To control HR of rapid AF by landiolol in ptients with ADHF.To uptitrate landiolol by the effectiveness of HR reduction and hemodynamic improvement.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.LVEF<40% 2.atrial tachyarrhtthmia with HR >120/min 3.being with Lnadiolol treatment

Exclusion criteria

Exclusion criteria: 1.extremely hemodynamically disruption 2.no standard treatment for heart failure 3.excess dehydration or abnormal electrolysis without any appropriate treatment 4.systolic blood pressure <80mmHg 5.apparent cardiogenic shock 6.pregnant 7.thyroid or adrenal disease

Design outcomes

Primary

Measure	Time frame
Heart rate reduction and hemodynamic improvements	—

Secondary

Measure	Time frame
Safety Prognosis and examine the role of HR reduction on the prognosis.	—

Countries

Japan

Contacts

Public ContactNoriaki Iwahashi

Yokohama City University Medical Center Diision of Cardiology

wsnorikun@yahoo.co.jp045-261-5656

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026