Small droperidol dose decreases desflurane concentration needed during breast cancer surgery: randomized double-blind study

Small droperidol dose decreases desflurane concentration needed during breast cancer surgery: randomized double-blind study - Droperidol and desflurane in breast surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020064

Enrollment

Registered

2015-12-03

Start date

2014-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer surgery

Interventions

Either droperidol0.02mg/kg or saline placebo was administrated to patients 30 minutes after induction. During anesthesia, blinded anesthesiologists in charge maintained BIS values at 50 by modulating

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: mastectomy or quadrantectomy

Exclusion criteria

Exclusion criteria: reconstructive procedures

Design outcomes

Primary

Measure	Time frame
The primary endpoint was to investigate the saving effect of DHB on the consumption of desflurane	—

Secondary

Measure	Time frame
The secondary endpoint included circulatory parameters, the times from the end of surgery to extubation and discharge between the groups.	—

Countries

Japan

Contacts

Public ContactMaiko Satomoto

Tokyo Madical and Dental University Anesthesiology

satomoto.mane@tmd.ac.jp+81358035325

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026