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Effect of Acetaminophen in preventing postoperative shivering: A randomized, triple-blind, placebo-controlled study

Effect of Acetaminophen in preventing postoperative shivering: A randomized, triple-blind, placebo-controlled study - Effect of Acetaminophen in preventing postoperative shivering: A randomized, triple-blind, placebo-controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000020043
Enrollment
96
Registered
2015-12-02
Start date
2015-12-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who will have elective gynecologic surgery

Interventions

An administration of Acetaminophen dose: 15 mg/kg (max 1000 mg) duration of administration: 15 minutes timing: Primary dosage is performed just after an anesthetic induction. Secondary dosage is

Sponsors

University of the Ryukyus
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients who will have elective, gynecologic abdominal surgery Predicted surgical time is over 2 hour Patients' physical status(ASA) are 1 or 2 Patients without an impaired liver function Patients without disturbance of consciousness

Exclusion criteria

Exclusion criteria: Insufficient record and measurement Patients who refuse to participate this study Patient with suspicion of allergy of Acetaminophen Patient with acute toxicity of Lidocaine or Ropivacaine Patient require critical care and mechanical ventilation in ICU after surgery Patient who is determined to be excluded from the study due to any reason by the study doctor

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative shivering

Secondary

MeasureTime frame
The score of postoperative shivering The change of intraoperative and postoperative core temperature The incidence of postoperative nausea and vomitting The values of pain intensity measured on visual analog scales

Countries

Japan

Contacts

Public ContactTakahiro Tadokoro

University of the Ryukyus Department of Anesthesiology, Faculty of Medicine

rover2727@yahoo.co.jp0988952221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026