Healthy adults
Conditions
Interventions
Apply the formulation including an active ingredient to the half of facial skin twice daily for 12 weeks Apply the placebo formulation to the another half of facial skin twice daily for 12 weeks
Sponsors
EXAM CO.,LTD
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Healthy females
Exclusion criteria
Exclusion criteria: -Subjects with cutaneous symptoms of atopic dermatitis -Pregnancies and lactations -Subjects undergoing hormon therapy -Subjects participation in another clinical study accompanied by topical application of formulations and tape stripping or delipidation treatment to obtain experimantal dry skin to the sites to be studied within the past 1 month -Subjects deemed inappropriate to participate in this study by the parinciple investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of water content, transepidermal water loss, visual score and texture after the topical application for 4, 8, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of cell morphology and the composition of stratum corneum after the topical application for 4, 8, 12 weeks | — |
Countries
Japan
Contacts
Public ContactYukiyoshi Katsumata
EXAM CO., LTD Cosmetic Laboratory Department
Outcome results
None listed