Modified Simultaneous Integrated Boost Radiotherapy for Large tumor

Modified Simultaneous Integrated Boost Radiotherapy for Large tumor - Modified Simultaneous Integrated Boost Radiotherapy for Large tumor

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019944

Enrollment

Registered

2016-01-10

Start date

2016-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

More than 10 cm longest diameter or 5 cm shortest diameter clinically or pathologically visible malignant tumor

Interventions

Radiotherapy Up to tolerable dose to organ at risk i.e., (2Gy/fr to intestine and 5Gy/fr to tumor central zone) Total 100Gy/20fr to tumor central zone and 40Gy/20fr to intestinal tract

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Histologically or clinically diagnosed malignant tumor 2. Large measurable tumor more than 10 cm longest diameter or more than 5 cm shortest diameter

Exclusion criteria

Exclusion criteria: 1. Unable to obtain wrriten infromed consent 2. Unsuitable for treat due to severe co-mobidity or mental dysorder 3 Unsuitable for treatby Physicians perspection

Design outcomes

Primary

Measure	Time frame
Initial tumor response According to RECIST criteria (up to 6 months)	—

Secondary

Measure	Time frame
1) Toxicity 2) Local control 3) Cause specific survival rate 4) Overakk survival rate 5) QOL	—

Countries

Japan

Contacts

Public ContactHideya Yamazaki

Graduate School of Medical Science, Kyoto Prefectural University of Medicine Department of Radiology

hideya10@hotmail.com075-251-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026