An exploratory research of minute radiation myocardium disorder by the added electrocardiogram device.

An exploratory research of minute radiation myocardium disorder by the added electrocardiogram device. - An exploratory research of minute radiation myocardium disorder by the added electrocardiogram device.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019932

Enrollment

Registered

2015-12-15

Start date

2016-01-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

several cancers received irradiation to the chest

Interventions

Before RT, just after RT, 3 months after RT, 6 months after RT. the added electrocardiogram device echo-cardiogram MRI(if possible) 123I-BMIPP(if possible)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients who received thoracic radiotherapy, and unavoidable cardiac irradiation. age of 20 to 80 years old at the informed consent Eastern Cooperative Oncology Group performance status of 0 or 1 over 1 year prognosis written informed concent

Exclusion criteria

Exclusion criteria: under 1 year prognosis skin disease pacemaker claustrophobia drug hypersensitivity psychiatric disorder unstable angina and myocardial infarction not allowing participation into this protocol

Design outcomes

Primary

Measure	Time frame
the presence or absence of late potential by the added electrocardiogram before RT(control), just after RT, 3 months after RT, 6 months after RT 1. FQRS-D(Filtered QRS-Duration) more than 114ms 2. RMS40ms(Root-Mean-Square voltage of the signals in the last 40ms) less than 20uV 3. LAS40uV(the duration of the Low-Amplitude Signal after the voltage decreased to less than 40uV) more than 38msec LP positive means more than 2 items abnormality.	—

Measure

Time frame

the presence or absence of late potential by the added electrocardiogram before RT(control), just after RT, 3 months after RT, 6 months after RT 1. FQRS-D(Filtered QRS-Duration) more than 114ms 2. RMS40ms(Root-Mean-Square voltage of the signals in the last 40ms) less than 20uV 3. LAS40uV(the duration of the Low-Amplitude Signal after the voltage decreased to less than 40uV) more than 38msec LP positive means more than 2 items abnormality.

—

Secondary

Measure	Time frame
Echocardiogram; ejection fraction, E/E, TEI index MRI; late enhancement of ventricular septum 123I-BMIPP; down take of 123I-BMIPP	—

Countries

Japan

Contacts

Public ContactTohru Okada

Nagoya University Graduate school of Medicine Department of Radiology

tohruokada@med.nagoya-u.ac.jp052-744-2328

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026