Multicenter, prospective study on respiratory stability through recovery process from deterioration of heart failure in patients with chronic heart failure.

Multicenter, prospective study on respiratory stability through recovery process from deterioration of heart failure in patients with chronic heart failure. - Prospective study on respiratory stability through recovery process from deterioration of heart failure (PROST)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019905

Enrollment

Registered

2015-11-24

Start date

2015-11-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Heart Failure

Interventions

1) Overnight respiratory measurement (sleep study) The overnight respiratory measurement is carried out using a portable polygraph (type 3), SAS-3200 during the bedtime. The air flow is measured usin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with chronic heart failure are hospitalizing due to heart failure deterioration. 2) Patients in whom the investigator considered that respiratory intervention (such as positive ventilation or oxygen inhalation etc.) is unnecessary or will be unnecessary. 3) Patient with 20 years or older. 4) Patients or proxy providing the written informed consent.

Exclusion criteria

Exclusion criteria: 1) Patient considered to be not able to measure overnight respiratory (such as rhinostenosis). 2) Patients within three months from the onset of acute coronary syndrome (ACS). 3) Patients without an independent walking before the hospitalization. 4) Patients having a chronic respiratory failure or chronic obstructive pulmonary disease. 5) Patients with a central nervous disorder by stroke or injury. 6) Patients with hemodialysis. 7) Patients whose QOL is limited by malignant tumor or other diseases. 8) Patients who are inability or doubted for an agreement before deterioration of heart failure. 9) Any other patients who are regarded as unsuitable for this study by the investigators.

Design outcomes

Primary

Measure	Time frame
1)Change of a mean RSI calculated for the overnight respiratory measurement. 2)Change of RSI calculated for the daytime brief respiratory measurement.	—

Secondary

Measure	Time frame
Change of a median RSI calculated for the overnight respiratory measurement. Change of the mean and a standard deviation of a respiratory cycle, a mean ventilatory frequency, apnea hypopnea index (AHI), 3% oxygen desaturation index (ODI), a mean percutaneous oxygen saturation (SpO2) calculated for the overnight respiratory measurement. Change of the mean and the standard deviation of respiratory cycle, the ventilatory frequency, a mean tidal volume, an end-tidal carbon dioxide concentration (ETCO2) and an end-tidal oxygen concentration (ETO2) calculated for the daytime brief respiratory measurement.	—

Measure

Time frame

Change of a median RSI calculated for the overnight respiratory measurement. Change of the mean and a standard deviation of a respiratory cycle, a mean ventilatory frequency, apnea hypopnea index (AHI), 3% oxygen desaturation index (ODI), a mean percutaneous oxygen saturation (SpO2) calculated for the overnight respiratory measurement. Change of the mean and the standard deviation of respiratory cycle, the ventilatory frequency, a mean tidal volume, an end-tidal carbon dioxide concentration (ETCO2) and an end-tidal oxygen concentration (ETO2) calculated for the daytime brief respiratory measurement.

—

Countries

Japan

Contacts

Public ContactHidetsugu Asanoi

Imizu Municipal Hospital Department of Internal Medicine/Cardiology

hasanoi@kmh.biglobe.ne.jp0766-82-8100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026