Clinical study of the changes in platelet function and coagulation in insulin tolerance test

Clinical study of the changes in platelet function and coagulation in insulin tolerance test - Clinical study of the changes in platelet function and coagulation in insulin tolerance test

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019899

Enrollment

Registered

2015-11-23

Start date

2015-01-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who insulin tolerance test is determined to be necessary for pituitary function assessment

Exclusion criteria

Exclusion criteria: 65 years of age or older patients, Patients with a history of ischemic heart disease and seizures Patients who has oral anti-platelet drug or anticoagulant drug

Design outcomes

Primary

Measure	Time frame
AUC10, area under curve until 10 min for PL chip on T-TAS(Total Thrombus-formation Analysis System) and plasma catecholamines at 0min,15min,30min,60min, 90min, 120min before and after insulin load	—

Secondary

Measure	Time frame
1)plasma PAI-1(plasminogen activator inhibitor-1) 2) P-selectin and PAC-1 by flowcytometry	—

Countries

Japan

Contacts

Public ContactKiyoaki Yamamoto

Kagoshima University Graduate School of Medical and Dental Sciences Department of Diabetes and Endocrinology

kgmgt942@ybb.ne.jp099-275-6478

Outcome results