Analysis of inflammatory cells, soluble factors, molecules as mediators of retinal neural dysfunction and death

Analysis of inflammatory cells, soluble factors, molecules as mediators of retinal neural dysfunction and death - Analysis of molecular mechanisms of retinal neural dysfunction

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019837

Enrollment

260

Registered

2015-11-18

Start date

2014-05-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinal dysfunction, retinal degeneration

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Retinal degenration with little pigmentation or atypical Retinal degeneration or retinal degeneration with causative mutations unidentified. Intraocular inflammation. Patient strongly suspected of having reduced vision, signs of retinal structual or electrophysiological abnormalities.

Exclusion criteria

Exclusion criteria: patients that were judged to be inappropriated by the physician. Intraocular surgery within 2 weeks.

Design outcomes

Primary

Measure	Time frame
Whether one can replicate the pathology in mice using patient's serum.	—

Secondary

Measure	Time frame
Identification of autoantigen for autoimmune retinopathy	—

Countries

Japan

Contacts

Public ContactKOJI Nishiguchi

Tohoku University Graduate School of Medicine Department of Advanced Ophthalmic Medicine

nishiguchi@oph.med.tohoku.ac.jp+81-22-717-7294

Outcome results