Assessing analgesia in single and repeated administrations of acetaminophen for postoperative pain after gynecologic laparoscopic surgery

Assessing analgesia in single and repeated administrations of acetaminophen for postoperative pain after gynecologic laparoscopic surgery - Repeated vs single administrations of acetaminophen (gynecologic laparoscopic surgery)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019775

Enrollment

Registered

2015-11-16

Start date

2014-10-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian desease

Interventions

Patients in group R were administrated IV 1 g acetaminophen 4 times per day for 2 days postoperatively. Patients in group S were administrated IV 1 g acetaminophen only once at the end of surgery.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists physical status 1-2 who were scheduled to undergo elective gynecologic laparoscopic surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1) Weighed < 40 or > 100 kg 2) Pregnancy 3) Having neurological, cardiovascular, and respiratory complications. 4) Allergy to amide local anesthetics or opioids4 5) Psychoactive medications 6) Hepatic or renal failure 7) Inability to understand the pain scale 8) Not obtained informed consent

Design outcomes

Primary

Measure	Time frame
1) postoperative pain score (numerical rating scale: NRS) at 2, 4 hour at postoperative day (POD) 0, AAM and PM at POD 1 and 2 2) supplemental analgesia for 2 days	—

Secondary

Measure	Time frame
1) postoperative nausea and vomiting for 2 days 2) satisfaction of the patient using NRS at POD 2	—

Countries

Japan

Contacts

Public ContactYukitoshi Niiyama

Sapporo Medical University, School of Medicine Department of Anesthesiology

niiyama@sapmed.ac.jp011-611-2111(3568)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026