Analgesic effect of peripheral nerve block after gynecological lower abdominal surgery; concentration versus volume of local anesthetic.A prospective randomized trial.

Analgesic effect of peripheral nerve block after gynecological lower abdominal surgery; concentration versus volume of local anesthetic.A prospective randomized trial. - Analgesic effect of peripheral nerve block after gynecological lower abdominal surgery; concentration versus volume of local anesthetic.A prospective randomized trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019766

Enrollment

Registered

2015-11-12

Start date

2013-10-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are scheduled for gynecological lower abdominal surgery.

Interventions

Patinets will receive ultrasound-guided transversus abdominis plane block using 0.4%,3 mg/kg of ropivacaine. Patinets will receive ultrasound-guided transversus abdominis plane block using 0.2%,3 mg/k

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1)Patients who are scheduled for gynecological lower abdominal surgery in Nagoya university hospital. 2)American Society of Anethesiologists physical status in 1, 2 or 3. 3)Patients who can evaluate the pain using visual analogue scale(VAS) 4)Patients who can give written informed consent,

Exclusion criteria

Exclusion criteria: 1)Patients who have stomach ulcer, renal failure or liver failure. 2)Patients who have allergy to the drugs which will going to use in this trial. 3)Patients who have severe obesity over BMI 30. 4)Patients who have contraindication of Ropivacaine. 5)Patients who are regarded ineligible by doctors with ather reasons.

Design outcomes

Primary

Measure	Time frame
Postoperative morphine consumption after 4, 24, 48, and 72 hours.Using patient controlled analgesia.	—

Secondary

Measure	Time frame
Pain:Visual analogue scale(VAS) at rest and at cough after 4, 24, 48, and 72 hours postoperation. Adverse event. Blood pressure and SpOs after 4,24,48 and 72 hours postoperation, Ropivacaine plasma concentration after 0,15,30,45,60 and 120 mins after transversus abdominis plane block.	—

Countries

Japan

Contacts

Public ContactAkiko Akane

Nagoya University Hospital Department of Anethesiology

a-ohashi@med.nagoya-u.ac.jp052-744-2340

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026