Resectable pancreatic adenocarcinoma, borderline resectable pancreatic adenocarcinoma with portal vein invasion or arterial invasion
Conditions
Interventions
Sponsors
Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Histologically proven pancreatic adenocarcinoma (2) Age between 20 and 85 years (3) ECOG performance status of 0 or 1 (4)Resectable and Borderline resectable pancreatic cancer (NCCN criteria) (5) Adequate hematologic, renal, hepatic and respiratory function (6) Written informed consent (7)Operation performed in Nagoya University Hospital and Kansai Medical University
Exclusion criteria
Exclusion criteria: (1) Unresectable pancreatic cancer (NCCN criteria) (2)Tumors with encasement or stenosis of the arteries, those abutted with the celiac axis (3) Hematologic, renal, hepatic and respiratory dysfunction (4)Active infections (5) Severe cardiac disorder, renal disorder, liver disorder, ulcer with bleeding, intestinal tract paralysis, uncontrollable diabetes mellitus (6) Presence of pleural effusion or ascites requiring drainage (7)Pregnant females or nursing mothers who can not stop lactation. Patients or partners, who don't attempt to doing contraception during the study period. (8) Severe mental disorder (9) Severe drug hypersensitivity (10) As determined by the principal investigator or the sub-investigator the subject is not adequate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival, short-term clinic benefit, the effect of NACRT, adverse events | — |
Countries
Japan
Contacts
Public ContactTsutomu Fujii
Nagoya University Graduate School of Medicine Gastroenterological Surgery (Surgery II)
Outcome results
None listed