Research on the pathogenesis of autosomal dominant polycystic kidney disease

Research on the pathogenesis of autosomal dominant polycystic kidney disease - ADPKD-Hokkaido-1

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019614

Enrollment

250

Registered

2015-11-02

Start date

2015-11-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autosomal dominant polycystic kidney disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of ADPKD who have visited or been admitted to Hokkaido University Hospital or its related hospitals at least twice Patients who meet the following criterion if blood and/or urine samples will be collected: - Patients who are capable to consent

Exclusion criteria

Exclusion criteria: Patients who meet the following criterion if blood and/or urine samples will be collected: - Patients who, in the opinion of the investigator, are inappropriate for the study

Design outcomes

Primary

Measure	Time frame
Evaluation of factors that may affect the progression of ADPKD (annual percentage change in kidney volume)	—

Secondary

Measure	Time frame
Evaluation of factors that may affect the progression of ADPKD (annual change in eGFR) Exploration of factors that may affect the onset of ADPKD-related events (cerebral aneurysm, hypertension, urolithiasis, renal pain, macroscopic hematuria, cyst infection, urinary tract infection, proteinuria, dialysis, and other ADPKD-related events) and other major events (e.g., cardiovascular events) Comparison of genetic background information between subjects and healthy adults	—

Measure

Time frame

Evaluation of factors that may affect the progression of ADPKD (annual change in eGFR) Exploration of factors that may affect the onset of ADPKD-related events (cerebral aneurysm, hypertension, urolithiasis, renal pain, macroscopic hematuria, cyst infection, urinary tract infection, proteinuria, dialysis, and other ADPKD-related events) and other major events (e.g., cardiovascular events) Comparison of genetic background information between subjects and healthy adults

—

Countries

Japan

Contacts

Public ContactSaori Nishio

Hokkaido University School of Medicine Department of Medicine II

saorin@med.hokudai.ac.jp011-706-5915

Outcome results