Effect of general anesthesia with sevoflurane at age-adjusted concentration on electrocorticography, compared with 2.5% in patients with intractable epilepsy

Effect of general anesthesia with sevoflurane at age-adjusted concentration on electrocorticography, compared with 2.5% in patients with intractable epilepsy - Effect of sevoflurane concentration on the electrocorticography

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019603

Enrollment

Registered

2015-11-02

Start date

2015-11-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intractable epilepsy

Interventions

Electrocorticogram is recorded with the end-tidal concentration of sevoflurane at 1.5 x age-adjusted minimum alveolar concentration, followed by recording with the end-tidal concentration of sevoflura

age.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing surgical treatment of intractable epilepsy with American Society of Anesthesiologists physical status I-III

Exclusion criteria

Exclusion criteria: Patients with ischemic heart disease or decreased cardiac function with left ventricular ejection fraction equal to or less than 40%

Design outcomes

Primary

Measure	Time frame
The frequency of spikes during anesthesia	—

Secondary

Measure	Time frame
The area where spikes are detected during anesthesia	—

Countries

Japan

Contacts

Public ContactYutaka Oda

Osaka City General Hospital Anesthesiology

odayou@s5.dion.ne.jp+81-6-6929-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026