Effect of Leucine-rich essential amino acid mixture food (amino care jelly Leucine 40) on exercise therapy in NAFLD (Pilot Trial)

Effect of Leucine-rich essential amino acid mixture food (amino care jelly Leucine 40) on exercise therapy in NAFLD (Pilot Trial) - Amino L40 Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019598

Enrollment

Registered

2015-12-01

Start date

2015-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic fatty liver disease

Interventions

(1) Diet and exercise therapy (+) amino care jelly Leucine 40 (-) 0 - 12 weeks (2) Diet and exercise therapy (+) amino care jelly Leucine 40 (100g / day) (+) 12 - 24 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Cases were clinically diagnosed as NAFLD (2) More than 50 years of age and less than 80 years (3) Informed consent is obtained by sentence

Exclusion criteria

Exclusion criteria: (1) Patients with viral hepatitis (2) Liver cirrhosis patients (3) Patients with malignant tumor (not included after radical) (4) Individuals with a history of cardiovascular or cerebrovascular Diseases (5) Severe liver disease (6) Severe renal disease (7) Patients with rush by "amino care jelly Leucine 40"

Design outcomes

Primary

Measure	Time frame
Longitudinal change in skeletal muscle tissue fat accumulation by IMAC	—

Secondary

Measure	Time frame
Skeletal muscle volume, insulin resistance, liver function, serum lipid, glucose metabolism, inflammatory markers, and each parameter	—

Countries

Japan

Contacts

Public ContactHirokazu Takahashi

Faculty of Medicine, Saga University Department of Internal Medicine

takahas2@cc.saga-u.ac.jp0952-34-2362

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026