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Quinidine sulfate administration for intractable epilepsy with KCNT1 gene mutation

Quinidine sulfate administration for intractable epilepsy with KCNT1 gene mutation - Quinidine sulfate administration for intractable epilepsy with KCNT1 gene mutation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000019594
Enrollment
10
Registered
2015-11-02
Start date
2015-11-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intractable epilepsy with KCNT1 gene mutation

Interventions

Quinidine sulfate administration

Sponsors

NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients of intractable epilepsy with KCNT1 gene mutation

Exclusion criteria

Exclusion criteria: The patient who is judged by the patient's physician as unsuitable for participating in this study.

Design outcomes

Primary

MeasureTime frame
Change in frequency of epileptic seizures

Secondary

MeasureTime frame
Change in severity of epileptic seizures. Change in EEG finding. Change in psychomotor development.

Countries

Japan

Contacts

Public ContactKatsumi IMAI

NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders Department of Epileptology

imaik-1@hosp.go.jp054-245-5446

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026