To reveal a way to optimize the absorption of lycopene 1.The comparing taking tomato juice with raw tomato 2.The most appropriate timing

To reveal a way to optimize the absorption of lycopene 1.The comparing taking tomato juice with raw tomato 2.The most appropriate timing - To reveal a way to optimize the absorption of lycopene

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019534

Enrollment

Registered

2015-10-30

Start date

2015-10-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

&lt

Period 1&gt

Food: Tomato juice Injection period: Single Dose: 160 mL (Lycopene 16 mg)/ 1 can Time: Evening Wash-out period: 1 week (between period 1 and period 2) &lt

Period 2&gt

Food: Tomato juice Injection period: Single Dose: 160 mL (Lycopene 16 mg)/ 1 can Time: Afternoon Wash-out period: 1 week (between period 2 and period 3) &lt

Period 3&gt

Food: Tomato juice Injection period: Single Dose: 160 mL (Lycopene 16 mg)/ 1 can Time: Morning Wash-out period: 1 week (between period 3 and period 4) &lt

Period 4&gt

Food: Raw tomato Injection period: Single Dose: About 320 g (Lycopene 16 mg) Time: Morning

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People who satisfy the following conditions will be required. 1) Who do not fit key exclusion criteria 2) Who are judged suitable for this study by principal investigator and commissioned researchers.

Exclusion criteria

Exclusion criteria: People who satisfy any of the following conditions will be excluded. 1) Who show hypercholesterolemia or hypertriglyceridemia 2) Who show something wrong in the liver function 3) Who have a marked surgical history of digestive system or have some problems in the respiratory system or the heart 4) Who show low absorption of lycopene (i.e. who show lower amount of lycopene change in the serum than 0.025 microM at 6h after taking tomato juice 5) Who do not have a habit of taking three meals in a day 6) Who are pregnant or breastfeeding, or desires to get pregnant during the study period 7) Who have a tomato allergy 8) Who have a smoking habit 9) Who join other studies 10) Who do not obey the study rule 11) Who are judged unsuitable for this study by principal investigator

Design outcomes

Primary

Measure	Time frame
Lycopene concentration in chylomicron before and 2,4,6,12 h after taking the intervention food. (measured value, amount of the change, the area under the curve)	—

Countries

Japan

Contacts

Public ContactYudai Aoki

Kagome CO.,LTD. Innovation Division

Yudai_Aoki@kagome.co.jp0287-36-2935

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026