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Examination of the procedures for suppressing endotracheal-induced adverse effects such as hemodynamic changes during intubation.

Examination of the procedures for suppressing endotracheal-induced adverse effects such as hemodynamic changes during intubation. - Examination of the procedures for suppressing endotracheal-induced adverse effects such as hemodynamic changes during intubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000019515
Enrollment
60
Registered
2015-10-28
Start date
2015-10-28
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients (ASA physical status I or II) who undergo surgeries under general anesthesia

Interventions

Laryngotrachal application of lidocaine before intubation. Laryngotrachal application of alkalized lidocaine before intubation. Laryngotrachal application of saline before intubation.

Sponsors

Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who required a tracheal intubation during general anesthesia.

Exclusion criteria

Exclusion criteria: Patients with anticipated difficult airway, patients who required a vasoactive agents after end of surgery, patients who were pretreated with beta-blockers.

Design outcomes

Primary

MeasureTime frame
Changes in blood pressure and heart rate during tracheal intubation.—

Secondary

MeasureTime frame
The degree of sore throat assessed by using a visual analogue scale (VAS, 0-100 mm) and hoarseness, dysphonea, nausea and vomitting are systematically evaluated as present or absent just after and at 15 minutes and 24 hours after extubation.—

Countries

Japan

Contacts

Public ContactKumiko Ishida

Shinshu University School of Medicine Department of Anesthesiology and Resuscitology

kumiko_m@shinshu-u.ac.jp0263372670

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026