Comparison of Autonomic Nerve Function by Three Procedures including PTAV, TAVR and TAVR in Patients with Severe Aortic Stenosis

Comparison of Autonomic Nerve Function by Three Procedures including PTAV, TAVR and TAVR in Patients with Severe Aortic Stenosis - Comparison of improvement on Autonomic Nerve function by 3 interventional treaments for AS patinets

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019508

Enrollment

Registered

2015-10-26

Start date

2015-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Valvar Stenosis

Interventions

SAVR TAVR PTAV

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Symptomatic AS patients who were admitted in our hospital to schedule PTAV, TAVR or SAVR. AS was diagnosed based on JCS Guideline

Exclusion criteria

Exclusion criteria: 1.Patients with hemodialysis 2.patients with prior history of Myocardial infarction within a month 3. patients with prior history of cerebrovascular events within 6 months 4.patients with LVEF<20%

Design outcomes

Primary

Measure	Time frame
To compared the improvement of autonomic nerve activity by 11C-HED-PET/CT among 3 procedures (SAVR,TAVR,PTAV), pre, after 2 weeks, after 6months,respectively.	—

Countries

Japan

Contacts

Public ContactMamoru Sakakibara

Hokkaido University Graduate School of Medicine Department of Cardiovascular Medicine

mike.s@ninus.ocn.ne.jp011-706-6973

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026