Oral immunotherapy for children with egg allergy: a randomized controlled trial

Oral immunotherapy for children with egg allergy: a randomized controlled trial - Oral immunotherapy for egg allergy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019489

Enrollment

Registered

2015-12-01

Start date

2015-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergy (egg)

Interventions

Oral immunotherapy with egg Oral immunotherapy with egg after 6 months of elimination diet

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Egg allergy patients with threshold of 2 g or more, and 10 g or less in oral food challenge

Exclusion criteria

Exclusion criteria: (1)History of heart, liver and/or renal diseases (2)Poorly controlled bronchial asthma and/or atopic dermatitis (3)Patients during oral immunotherapy for other food allergen (4)Patients whom the doctor assess ineligible

Design outcomes

Primary

Measure	Time frame
The proportion of patients with negative results of egg oral food challenge	—

Secondary

Measure	Time frame
(1) Change in threshold dose of oral food challenge before and after oral immunotherapy (at registration and 12 months of maintenance phase) in each subject (2)The frequency of allergic symptoms and rescue drug use (3)Change in allergen-specific immunoglobulin (4)Change in QOL by questionnaire	—

Countries

Japan

Contacts

Public ContactMayumi Sugimoto

Tokushima University Hospital Department of Pediatrics

sugimoto.mayumi@tokushima-u.ac.jp088-633-7135

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026