Acne vulgaris
Conditions
Interventions
punch biopsy on acne and non-acne regions
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1_Males between the ages of 18 and 45. 2_Subjects with acne, papule and/or pustule, on face, shoulder, chest and back, or healthy persons. 3_Who agrees about a blood test of HIV and hepatitis B and C. 4_Who agrees about the punch biopsy on acne and non-acne regions 5_Who is willing to accept blood drawn, measurement of sebum secretion and collection of the sebum and skin flora. 6_Who agrees not to wash the face on the days of clinical study. 7_Who agrees not to eat anything after 22 o'clock of the day immediately before his biopsy 8_Who is fluent in English and can read, understand and sign an IRB approved Informed Consent form. 9_Who is available for all study visits.
Exclusion criteria
Exclusion criteria: 1_Individuals who contract diabetes, HIV/AIDS or autoimmune disorders, and hepatitis B or C. 2_Individuals with cuts, lacerations, abrasions, or bruises on the biopsy sites 3_Individuals with tattoos on the biopsy sites. 4_Individuals who participated in other clinical study within 28days. 5_Individuals with allergies (self-reported) to wound dressings and adhesives, latex allergy or allergies towards the local anesthetic. 6_Individuals with any relevant past or present medical history which may affect the study results or may lead to increased risk to the subject in the judgment of the Sub-Investigator. 7_Individuals who use prescription medication or OTC topical medication at the biopsy site(s). 8_Individuals with needle phobia. 9_Individuals with self-reported problems in wound healing and/or disposition to develop extensive scars (keloids, hypertrophic wounds). 10_Individuals who are not prepared to give written informed consent 11_Individuals receiving medical treatment that, in the opinion of the Sub-Investigator, may interfere with this study. 12_Individuals taking medications, that in the opinion of the Sub-Investigator could interfere with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Collection of skin samples with or without acne vulgaris. Evaluation of the content of sebum secretion and collection of sebum and skin flora. | — |
Countries
North America
Contacts
Public ContactTakayoshi Inoue
Kao Corporation R&D -Core Technology- Biological Science Research
Outcome results
None listed