Relationship of laughter with mood/emotion and cortisol and dehydroepiandrosterone (DHEA) secretion: intervention study

Relationship of laughter with mood/emotion and cortisol and dehydroepiandrosterone (DHEA) secretion: intervention study - Laughter, mood/emotion, and cortisol/DHEA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019409

Enrollment

120

Registered

2015-10-28

Start date

2015-10-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N/A (healthy people)

Interventions

Spontaneous laughter: watching a comedy movie &quot

The Dictator&quot

for the first 40 minutes, a single-time exposure in a day, not repetitive. Simulated laughter: laughter yoga, a 40-minute practice, a single-time exposure in a day, not repetitive. Reading books on f

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 3rd-year medical student of Fujita Health University School of Medicine

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Taking medicine that could affects cortisol/DHEA secretion, such as estrogen, oral contraceptive, antipsychotic, and antidepressant

Design outcomes

Primary

Measure	Time frame
Mood/emotion (tension, depression, anger, vitality, fatigue, and confusion) and salivary cortisol and DHEA right before, right after, and 30 minutes after the intervention	—

Countries

Japan

Contacts

Public ContactAtsuhiko Ota

Fujita Health University School of Medicine Department of Public Healt

ohtaa@fujita-hu.ac.jp0562-93-2453

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026