Perioperative pain in coronary artery bypass graft surgery
Conditions
Interventions
In paracetamol group 15 minutes before induction of anesthesia 1 g intravenous paracetamol in 50 cc normal saline solution was infused to the patient within 15 minutes. Next dose of paracetamol was
Sponsors
Isfahan university of medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for the study were: undergoing elective surgery CABG, the individual agreement to participate in the study, age 40 to 70 years, not having liver failure (Serum bilirubin greater than 1.8 mg per deciliter and aspartate and alanine aminotransfraz more than 1.5 times of the upper limit of normal), not having renal failure (serum creatinine greater than 2 mg per deciliter), not addictive to opioid drugs and psychotropic substances, and having cardiac ejection fraction greater than 30%.,
Exclusion criteria
Exclusion criteria: Excessive bleeding after surgery (more than 150 ml for the first two hours), having other surgeries in addition to coronary artery bypass surgery such as repair or replacement of heart valves, repeated surgery, and the need for aortic balloon support.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preemptive administration of paracetamol and continue to be administered in the postoperative treatment with prescription of opioids drugs will improved quality of pain control after coronary artery bypass surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1- the potency is not enough to reduce the need for narcotics and sedatives drugs and eliminate their side effects. 2- no additional liver damages 3- Hemodynamic stability | — |
Countries
Asia(except Japan)
Contacts
Public ContactMojtaba mansouri
Isfahan university of medical sciences Anesthesiology and Critical Care Research Center, Department of Anesthesiology
Outcome results
None listed