Evaluation of efficacy and safety in bFGF injection to treat severe vocal fold lesions and vocal fold paralysis.

Evaluation of efficacy and safety in bFGF injection to treat severe vocal fold lesions and vocal fold paralysis. - bFGF injection for vocal fold lesions.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019347

Enrollment

100

Registered

2015-10-16

Start date

2015-08-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vocal fold atrophy,vocal fold sulcus,vocal fold scars,vocal fold paralysis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: vocal fold lesions and vocal fold paralysis causing severe hoarseness maintain more than 6 months.

Exclusion criteria

Exclusion criteria: The subjects with obvious decrease in cardiac function, respiratory function, or hepatic dysfunction in preoperative examinations such as blood sampling, electrocardiogram, or chest x-ray within 3 months. The subjects with vital signs such as heart rate, blood oxygen saturation, and blood pressure are abnormal on the day of surgery. The subjects with other laryngeal disease. The subjects with a history of laryngeal cancer The subjects with drug allergy

Design outcomes

Primary

Measure	Time frame
Improvement of Phonological Outcome	—

Secondary

Measure	Time frame
Improvement of vocal fold vibration Improvement of Aerodynamic assessment	—

Countries

Japan

Contacts

Public ContactWatanabe Yusuke

International University of Health and Welfare Tokyo Voice Center

vetchy2@yahoo.co.jp03-3402-3151

Outcome results