Preliminary study for non-invasive measurement of estrogen receptor by [18F]FES-PET/CT

Preliminary study for non-invasive measurement of estrogen receptor by [18F]FES-PET/CT - Measurement of estrogen receptor by FES-PET/CT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019336

Enrollment

Registered

2015-11-01

Start date

2015-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

18F-FES PET/CT, intravenous injection of 3.7MBq/kg of 18F-FES (max. 370MBq)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patient who is diagnosed as breast cancer 2) Patient who has performed, or who will be perform pathological estrogen receptor evaluation in our hospital 3) Patient who have completed the written informed consent

Exclusion criteria

Exclusion criteria: 1) Patient who is pregnant or who has the possibility of pregnancy 2) Patient who have difficulty in performing PET/CT exam by the severe pain or bad condition 3) Patient who are determined as not appropriate for attending this study by the investigators

Design outcomes

Primary

Measure	Time frame
a) Validity of PET imaging process, b) relationship between the uptake in 18F-FES PET/CT and the pathological expression of estrogen receptor at primary lesion of breast cancer, and c) relationship between the uptake in 18F-FES PET/CT and the results of other imaging modalities, are evaluated by the visual comparison by radiologists and statistical analysis by the results of pathology and other imaging modalities, when 18F-FES PET/CT images of all the cases will be acquired.	—

Measure

Time frame

a) Validity of PET imaging process, b) relationship between the uptake in 18F-FES PET/CT and the pathological expression of estrogen receptor at primary lesion of breast cancer, and c) relationship between the uptake in 18F-FES PET/CT and the results of other imaging modalities, are evaluated by the visual comparison by radiologists and statistical analysis by the results of pathology and other imaging modalities, when 18F-FES PET/CT images of all the cases will be acquired.

—

Countries

Japan

Contacts

Public ContactTomohiko Yamane

Saitama Medical University International Medical Center Nuclear Medicine

yamane_t@saitama-med.ac.jp042-984-4111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026