Volume expanding effect and peripheral perfusion of 130 HES in the patients during perioperative period

Volume expanding effect and peripheral perfusion of 130 HES in the patients during perioperative period - Efficacy of 130 HES in the patients during perioperative period

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019332

Enrollment

120

Registered

2015-10-13

Start date

2015-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative patients

Interventions

Intravenous administration of 500 ml of 130 HES in 10 minutes Intravenous administration of 500 ml of 70 HES in 10 minutes Intravenous administration of 500 ml of bicarbonated Ringer solution in 10 mi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with 1-2 of ASA physical status in elective surgery.

Exclusion criteria

Exclusion criteria: Patients with cardiovascular disease, hemorrhage and/or dehydration.

Design outcomes

Primary

Measure	Time frame
Increase of circulation blood volume at 10 minutes after the administration of 130 HES, 70HES or bicarbonated Ringer solution.	—

Secondary

Measure	Time frame
Changes of blood pressure, heart rate, peripheral perfusion index and hemoglobin at 10 minutes after the administration of 130 HES, 70HES or bicarbonated Ringer solution.	—

Countries

Japan

Contacts

Public ContactHiroaki Toyama

Tohoku University Hospital Department of Anesthesiology

h-toyama@umin.ac.jp022-717-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026