Clinical studies on the mechanism of action of local anesthetic in the levorotatory S-(-)-isomers.

Clinical studies on the mechanism of action of local anesthetic in the levorotatory S-(-)-isomers. - The local anesthesics of levorotatory S-(-)-isomers mechanism of action

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019307

Enrollment

Registered

2015-10-13

Start date

2015-10-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic pain

Interventions

We performe subctaneous injection of 0.025 ~0.25% bupivacaine. We mesure the thresholds of pain sensation caused by von Frey hair or thermal stimulation. We mesure the thresholds of tactile sensati

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy volunteer

Exclusion criteria

Exclusion criteria: allergy of local anethetics

Design outcomes

Primary

Measure	Time frame
We investigate the difference of mechanical, thermal pain and mechanical detection thresholds between levobupivacaine and bupivacaine for 2 hours after injection.	—

Countries

Japan

Contacts

Public ContactSakamoto Akiyuki

Shinshu university school of medicine anesthesiology and resuscitology

akiyuki@shinshu-u.ac.jp0263372795

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026