Healthy adults
Conditions
Interventions
PET by [18F] FE-PE2I, SPECT by [123I] FP-CIT, neuromelanin MRI
Sponsors
Department of Neuropsychiatry, Nippon Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects who have the ability to provide informed consent and adhere to the protocol. Normal controls: - Without subjective cognitive impairment - Without past or current history of cognitive dysfunction - Without past or current history of disease and injury that influences the central nervous system - Without past history of smoking - Without taking psychotropic drug
Exclusion criteria
Exclusion criteria: - With past or current history of serious medical illness - With past or current history of severe liver disease, kidney disease, heart disease, allergy, or severe drug allergy - Subjects who has possibility of pregnancy or is breast-feeding - Subjects who has been exposed to radiation by job-related exposure or therapy in one year exceeding 15mSv - Subjects who received contrast or radioactive agent within two days of the examination. - Subjects who scheduled receiving contrast or radioactive agent the day after the examination. - Subjects who are judged as not suitable for participation in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the results of dopamine transporter PET and SPECT | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the results of dopamine transporter PET and neuromelanin MRI | — |
Countries
Japan
Contacts
Public ContactAmane Tateno
Nippon Medical School Department of Neuropsychiatry
Outcome results
None listed