Patients with mechanical ventilation in surgical intensive care unit.
Conditions
Interventions
High oxygen concentration Group High Flow Nasal Cannula is placed just before extubation with a fraction of inspired oxygen of 100% and a current flow of 40L/minute. Patients are manually ventilated
PaO2/FiO2 ratio is measured at 15 minutes before extubation, and the value of adjusted oxygen concentration is calculated so that the PaO2 should become 100mmHg. The same fraction of inspired oxygen a
Sponsors
Fukuyama City Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The adult patients in our surgical intensive care unit who are going to have endtrachal tubes extubated.
Exclusion criteria
Exclusion criteria: The patients who are not managed by anesthesiologists, those who undergo tracheotomy, those who use non-invasive positive ventilation after extubation and those who cannot use High Flow Nasal Cannula after extubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome The degree of atelectasis formation in one, three and five days after endtracheal extubation which are evaluated by blinded radiologists using the radiological atelectasis score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcome The incidence of the re-intubation and the initiation of of non-invasive positive airway ventilation within 5 days after extubation. Duration of intensive care unit. PaO2/FiO2 ratio in 15 minutes, 1 hour, 12 hours and 24 hours after extubation. Degree of SpO2 just after extubation (one to 15 minutes). | — |
Countries
Japan
Contacts
Public ContactKenzo Ishii
Fukuyama City Hospital Department of Anesthesiology and Oncological Pain Medicine
Outcome results
None listed