hepatocellular carcinoma
Conditions
Interventions
In cases where a large volume of normal hepatic parenchyma is expected to be damaged by ordinary chemoembolization, a microballoon catheter is used to temporarily occlude the artery perfusing the norm
Sponsors
University of Tsukuba Hospital
Ibaraki prefectural central hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Diagnosis of hepatocellular carcinoma according to EASL guideline 2)Chemoembolization is indicated. 3)Performance status of 0-2 4)Liver function of Child-pugh A or B 5)eGFR is 30mL/min/1.73m2 or more 6)Platelet count of 50,000 microL or more 7)No previous treatment or 4 weeks after the previous treatment 8)Informed consent is obtained.
Exclusion criteria
Exclusion criteria: 1)Rupture of hepatocellular carcinoma 2)History of surgical or endoscopic treatment of bile duct 3)Prominent arterioportal or arteriovenous shunts 4)Dissection or stenosis of 50% or more in the celiac trunk or hepatic artery 5)Hepatic coma or severe psychiatric disorder 6)Severe drug allergy including iodine contast allergy 7)Inadequate patients to undergo the procedure safely
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the safety of BACE, adverse events except for the side effects of chemoembolization are assessed according to SIR(Society of interventional radiology) standards of practice committee classification of complications by outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| The efficacy of BACE is assessed on contrast enhanced CT or MRI after 3 month according to RECICL classification. | — |
Countries
Japan
Contacts
Public ContactKensaku Mori
Faculty of Medicine, University of Tsukuba Department of Radiology
Outcome results
None listed