Risk factors of cerebral infarction in the elderly: Effects of aging and types of ischemic stroke

Risk factors of cerebral infarction in the elderly: Effects of aging and types of ischemic stroke - Risk factors of cerebral infarction in the elderly: Effects of aging and types of ischemic stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019148

Enrollment

300

Registered

2015-10-01

Start date

2015-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral infarction

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 300 acute stroke; 150 with an age of>75 and 150 of <75 (both 150 included atherosclerotic: ATI,cardiogenic: CEI and lacunar stroke: LS of 50 each)

Exclusion criteria

Exclusion criteria: non

Design outcomes

Primary

Measure	Time frame
We investigated several clinical parameters (height, body weight, body mass index (BMI), systolic blood pressure and diastolic blood pressure), some hemodynamic and cardiac parameters. The following variables were measured; serum lipid levels (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol and triglyceride), glycosylated hemoglobin (HbA1c) value, hemoglobin (Hb) value, serum total protein (TP) levels, albumin (Alb) level, renal function parameters (blood urea nitrogen, serum creatinine and estimated glemerular filtration rate (eGFR)), liver function parameters (serum aspartate aminotransferase and alanine aminotransferase). We also investigated cardiac parameters, including the presence/absence of left ventricular hypertrophy (LVH) as evaluated by 12-lead ECG, the cardiothoracic ratio (CTR) measured on a chest X-ray and left atrial dimension (LAD), left ventricular end-diastolic dimension (LVDd), left ventricular end-systolic diameter (LVESD), interventricular septum thickness (IVST), left ventricular posterior wall thickness (LVPWth), aortic dimension and ejection fraction (EF) measured on a cardiac echo. Similarly, we investigated the carotid artery plaque score by carotid echo to evaluate the risk factor of atherosclerosis.	—

Measure

Time frame

We investigated several clinical parameters (height, body weight, body mass index (BMI), systolic blood pressure and diastolic blood pressure), some hemodynamic and cardiac parameters. The following variables were measured; serum lipid levels (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol and triglyceride), glycosylated hemoglobin (HbA1c) value, hemoglobin (Hb) value, serum total protein (TP) levels, albumin (Alb) level, renal function parameters (blood urea nitrogen, serum creatinine and estimated glemerular filtration rate (eGFR)), liver function parameters (serum aspartate aminotransferase and alanine aminotransferase). We also investigated cardiac parameters, including the presence/absence of left ventricular hypertrophy (LVH) as evaluated by 12-lead ECG, the cardiothoracic ratio (CTR) measured on a chest X-ray and left atrial dimension (LAD), left ventricular end-diastolic dimension (LVDd), left ventricular end-systolic diameter (LVESD), interventricular septum thickness (IVST), left ventricular posterior wall thickness (LVPWth), aortic dimension and ejection fraction (EF) measured on a cardiac echo. Similarly, we investigated the carotid artery plaque score by carotid echo to evaluate the risk factor of atherosclerosis.

—

Countries

Japan

Contacts

Public ContactSayato Fukui

School of medicine, Tokai University Department of Physiology

sfukui@tsc.u-tokai.ac.jp0463-93-1121

Outcome results