Low dose dexmedetomidine inhibit post operative nausea and vomitting and shivering post brain tumor resection. Double Blind Randomized Control Trial

Low dose dexmedetomidine inhibit post operative nausea and vomitting and shivering post brain tumor resection. Double Blind Randomized Control Trial - The effect of low dose dexmedetomidine after neurosurgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000019139

Enrollment

100

Registered

2015-10-01

Start date

2015-12-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain tumor

Interventions

low dose dexmedetomidine is started at the timing of resection of brain tumor as 0.3 mcg/kg/hr of administration speed. Then it is administered totally 40ml. normal saline is started at the timing of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who planed brain tumor resection, and obtained informed consent for participation of this study.

Exclusion criteria

Exclusion criteria: under 18 years old, not obtained informed consent, transferred to ICU under ventilation, insufficient data.

Design outcomes

Primary

Measure	Time frame
the incidence of PONV.	—

Secondary

Measure	Time frame
The incidence of shivering and the variation of hemodynamics changes	—

Countries

Japan

Contacts

Public Contactshunsuke takaki

Yokohama City University Hospital Intensive Care Unit

shunty5323@gmail.com045-787-2918

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026