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Randamized control trial for the effect of preoperative carbohydrate loading on the post operative hyperglycemia and evaluatioin of time to eliminate gastric contents on the patients with colorectal cancer surgery

Randamized control trial for the effect of preoperative carbohydrate loading on the post operative hyperglycemia and evaluatioin of time to eliminate gastric contents on the patients with colorectal cancer surgery - The effect of preoperative carbohydrate loading on the postsurgical hyperglycemia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000019112
Enrollment
48
Registered
2015-10-01
Start date
2015-09-28
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

The control group: At preoperative night, patient drinks 800mL of water. From 2.5 to 3 hours before operation, patients drink 400mL of water. The 12.5% of carbohydrate group: At preoperative night, p

Sponsors

Kobe City Medical Center General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who require the colorectal cancer surgery and are able to eat orally and aged from 20 to 70. Obtained written consent to this study.

Exclusion criteria

Exclusion criteria: 1 With comorbidity and classed ASA 3 or over 2 With comorbidity of diabetes mellitus or their HbA1c is 6.5 or over. 3 With their BMI over 30 4 Patients who take steroids or other drugs which have possibility of influence to blood glucose 5 Patients who require steroids or other drugs which have possibility of influence to blood glucose 6 With abnormal gastrointestinal function. For example, pyloric stenosis or past history of gastric resection. 7 With chronic kidney disease.(estimated GFR<60)

Design outcomes

Primary

MeasureTime frame
Improvement of insulin resistance pre- and post- operation with HOMA-R Blood glucose Concentration of blood insulin

Secondary

MeasureTime frame
Time to first stool from operation Time to eat 'Gobugayu'.Gobugayu is Japanese Rice porridge cooked with water 10 % rice. Days to discharge hospital. Rates of reoperation Rates of readmission Postoperative mortality Rate of postoperative complication

Countries

Japan

Contacts

Public ContactNaoki Higashibeppu

Kobe City Medical Center General Hospital Department of Anesthesia and Critical Care

gashibe@kcho.jp0783024321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026