A long term assessment for factors having an impact on the patency of saphenous vein graft following coronary artery bypass grafting

A long term assessment for factors having an impact on the patency of saphenous vein graft following coronary artery bypass grafting - A long term assessment for factors having an impact on the patency of saphenous vein graft following coronary artery bypass grafting

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000019062

Enrollment

Registered

2015-09-18

Start date

2015-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic cardiac disease(effort angina pectoris,asymptomatic myocardial ischemia,acute coronary syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients meeting all of the following conditions will be included: 1) underwent coronary bypass grafting using the vein graft 2) between 20 and 85 years old 3) written consent for participation in the study

Exclusion criteria

Exclusion criteria: Patients meeting one of the following conditions will be excluded: 1) severe liver dysfunction 2) renal dysfunction (Cre>= 2.0mg/dL) 3) severe heart failure (NYHA/New York Heart Association stage III or severer) 4) malignancies or other diseases with poor prognosis 5) pregnant, lactating, and possibly pregnant women and those planning to become pregnant 6) judged as ineligible by clinical investigators

Design outcomes

Primary

Measure	Time frame
The patency of saphenous vein graft one year after CABG	—

Secondary

Measure	Time frame
1) Lumen area, intimal thickening and incidence of thrombus evaluated by OCT 2) Coronary flow velocity of saphenous vein graft 3) Value of inflammatory and vasoactive biomarker	—

Countries

Japan

Contacts

Public ContactYuichiro Nagano

Kobe University Graduate School of Medicine Division of Cardiovascular Medicine

y_nagano1981@yahoo.co.jp078-382-5111

Outcome results