Development of an ex vivo method for evaluation of the mitochondrial function

Development of an ex vivo method for evaluation of the mitochondrial function - An ex vivo evaluation method for mitochondria

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018993

Enrollment

Registered

2015-10-19

Start date

2015-10-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MELAS

Interventions

Blood sampling to detect the disease-activity of MELAS

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Typical clinical picture of MELAS (myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) with the specific muscle histology (RRF, SSV) and the gene alterations of mitochondrial DNA (A3243G)

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Confirming the specificity and sensitivity of the novel biomarker for the disease activities of MELAS, compared to those of the canonical biomarker, serum lactate or the ratio of lactate/pyruvate	—

Countries

Japan

Contacts

Public ContactYoshihide Sunada

Kawasaki Medical School Neurology

ysunada@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026