tendency toward constipation
Conditions
Interventions
intake of a test food containing with lactobacillus for 8 consecutive weeks
intake of a placebo for 8 consecutive weeks
Sponsors
TTC Co., Ltd
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Females from 20 to 64 years of age (2) Subjects with a tendency for constipation at three to five times of defecation per week
Exclusion criteria
Exclusion criteria: (1) Subjects who routinely takes foods or medicines containing of lactobacillus (2) Subjects who routinely takes foods or medicines which may influence bowel movement or skin (3) Subjects having diseases affecting bowel movement or a history of these diseases (4) Subjects who hase treated cosmetic care (5) Subjects who has treated cosmetic care except for measuring sites, or hormonal therapy for one year (6) Subjects who got a facial, a wash-rag, lost hair on measuring sites for one month ago, or plans these actions. (7) Subjects who washes the body using a nylon towel which provides strong skin irritation (8) Subjects who has the wound or inflammatory disease affecting the measuring skin (9) Subjects who has asthma or the possibility of asthma (10) Subjects who has being excepted to be developed the allergy symptoms on skin (11) Subjects who feels to trouble by rough skin around a menstruates (12) Subjects who is employed on a pre-dawn shift or on night duty more than 2 times (13) Subjects who is planned to go overseas (14) Subjects who has treatment or a history of serious disease or affecting a secretion of sex hormones (15) Subjects having possibilities for emerging allergy related to the study (16) Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on screening test (17) Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study (18) Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating (19) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (20) Subjects judged as unsuitable for the study by the investigator for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| moisture content of the stratum corneum, transepidermal water loss | — |
Secondary
| Measure | Time frame |
|---|---|
| defecation frequency, defecation days, stool output, fecal condition, skin questionnaire | — |
Countries
Japan
Contacts
Public ContactShinsuke Tsuji
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed