Ideopathic Sudden Sensorineural Hearing Loss (ISSHL)
Conditions
Interventions
Myringotomy is performed at the start of treatment. Gelatin sponge saturating dexamethasone is put in the tympanic cavity This procedure is performed after myrigotomy. Dexamethasone is injected int
Sponsors
Shin-ichi Kanemaru
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are diagnosed as ISSHL and who have some diseases showing below which would become worse by systemic steroids. Age ; elder than 75 years old Diabetes which is not controlled well Gastric or duodenum ulcer Severe infection ; virus hepatitis or tuberculosis etc. Severe bone disease; Idiopathic Osteonecrosis of Femoral Head etc. Sever heart disease Thrombosis ; cerebral thrombosis or deep vein thrombosis etc. Auto Immune disease Severe dermatoid disease; atopic dermatitis etc. Patients who are diagnosed as systemic steroid administration is improper for by other disease 2. Patients with ISSHL whose hearing loss has been not improved by systemic steroids and their hearing loss occurred within three weeks 3.Patients whom we get consent about this treatment Patients who meet the criteria 1 and 3 or the criteria 2 and 3 will be enrolled in this study.
Exclusion criteria
Exclusion criteria: 1.Patients who have anaphylaxis of dexamethasone 2.Patients who have middle ear infection obviously 3.Patients who have organic ear disease which would affect hearing loss; acoustic tumor, malformation of inner ear Patients who meet the either criteria will be excluded in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A hearing test is performed at the end of one course,one or two weeks, one, 2, 3 and 6 months after the treatment. The results of this treatment are compared with those of the cases with systemic steroids the historical control in the following items; cure rates, recovery rates and incidence of complications. | — |
Countries
Japan
Contacts
Public ContactShin-ichi Kanemaru
Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital Otolaryngolory, Head and Neck Surgery
Outcome results
None listed