Alteration of the permiability in Gastric tissue after successful eradication of Helicobacter pylori by the stimulation of gastric acid and bile acid

Alteration of the permiability in Gastric tissue after successful eradication of Helicobacter pylori by the stimulation of gastric acid and bile acid - The permiability in the post-eradication gastric mucosa

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018967

Enrollment

Registered

2015-10-01

Start date

2015-09-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

Congo-red chromoendoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: subjects with post-eradication gastric cancer which were pointed out after 24-months of the successful eradication

Exclusion criteria

Exclusion criteria: 1)subjects taking steroid, immunosupressive agents, NSAIDs, PPI within 1-month 2)subjects treated by surgery for upper GI tract 3)contraindication of biopsy 4)contrainducation of gastrin injection 5)pregnancy 6)severe illness 7)phychiatry

Design outcomes

Primary

Measure	Time frame
Difference in the alteration of gastric permeability by the stimulation of gastric acid and bile acid between atrophic mucosa and non-atrophic mucosa	—

Secondary

Measure	Time frame
Difference in the alteration of tight junction-associated cascades by the stimulation of gastric acid and bile acid between atrophic mucosa and non-atrophic mucosa	—

Countries

Japan

Contacts

Public ContactKaname Uno

Tohoku university Division of Gastroenterology

kaname-1@umin.ac.jp+81-22-717-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026