gastric cancer patients with pathological stage 1 and 2
Conditions
Interventions
None listed
Sponsors
Japanese Gastirc cancer association
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The gastric cancer patients with stage 1 or 2 2. Having a T-score over -2.5 measured by the DXA method within 4 weeks after the gastric resection 3. Patients shall not have medicaland treatment history of osteoporosis 4. Patients shall not have treatment history of Androgen receptor antagonists,Aromatase inhibitor,Insulin,corticosteroid or vitamin D 5. Patients shall not have treatment history of chemotherapy,radiation therapy or any gastric resection 6. Performance Status(ECOG) 0 or 1 7. Written informed consent will be obtained from all patients
Exclusion criteria
Exclusion criteria: 1.Hyperthyroidism,Hypothyroidism 2.Hyperparathyroidism,Hypoparathyroidism 3.Hypocalcemia,Hypercalcemia 4.Rheumatoid arthritis 5.Paget's disease of bone 6.Hyperprolactinemia 7.Chronic liver disease and Cirrhosis 8.Alcoholism 9.Chronic kidney disease and Renal insufficiency 10.Primary amenorrhea,Early menopause and the patients who have history of Oophorectomy before menopause 11.Patients determined to be inappropriate for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of the bone mineral dencity changes per year | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence rate of the new vertebral body fracture,the incidence rate of the fragility fracture,the incidence rate of osteoporosis,P1NP,sNTX,alkaline-phosphatase | — |
Countries
Japan
Contacts
Public ContactMotohiro Imano
Kinki University Faculty of Medicine Department of surgery
Outcome results
None listed