Knee osteoarthritis
Conditions
Interventions
Placebo drink(350ml/day for 12 weeks)+Daily exercise training for 12 weeks
Active drink(350ml/day for 12 weeks)+Daily exercise training for 12 weeks
Sponsors
Niigata Rehabilitation Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Knee OA subjects with Kellgren-Lawrence grade 2-3 Subjects who can perform muscle exercise Subjects who can take test drinks for 12 weeks Subjects who obtain doctor's permission for participation in this clinical study as a result of the medical examination Subjects who can follow directions of medical workers in this clinical study
Exclusion criteria
Exclusion criteria: Subjects who had injury of locomotor organ including fracture, tendon rupture,muscle strain,and so on in last 1 year Subjects who are not eligible due to physician's judgment Subjects whose family member is related to the competitor of Kao Corporation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JKOM score, Leg muscular power | — |
Secondary
| Measure | Time frame |
|---|---|
| physical performance test, cartilage metabolism markers, skeletal metabolism markers, inflammation markers, blood enzyme activities, blood hormone concentrations, blood metabolite concentrations | — |
Countries
Japan
Contacts
Public ContactTakashi Fushimi
Kao Corporation Biological Science Laboratory
Outcome results
None listed